Publications
Publications
* Select publications pre-2026
Tharp KM, Park S, Timblin GA, Richards AL, Berg JA, Twells NM, Riley NM, Peltan EL, Shon DJ, Stevenson E, Tsui CK, Palomba F, Lefebvre AEYT, Soens RW, Ayad NME, Hoeve-Scott JT, Healy K, Digman M, Dillin A, Bertozzi CR, Swaney DL, Mahal LK, Cantor JR, Paszek MJ, Weaver VM. The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism. Sci Adv. 2026 Aug 7;12(32):eaeb1136. DOI: 10.1126/sciadv.aeb1136
Zhang H*, Tsui CK*, Castillo JG, Kim EJY, Evangelista A, Liu H, Joe LK, Twells N, Robey EA, Mahal LK, DuPage M, Dillin A. Age-related remodeling of the sialoglycans dampens murine CD8(+) T cell function. Sci Adv. 2025 Sep 26;11(39):eadw6755. PubMed Central ID: PMC12467053. *Denotes equal contribution
Tsui CK†, Twells N, Durieux J, Doan E, Woo J, Khosrojerdi N, Brooks J, Kulepa A, Webster B, Mahal LK, Dillin A†. CRISPR screens and lectin microarrays identify high mannose N-glycan regulators. Nat Commun. 2024 Nov 18;15(1):9970. doi: 10.1038/s41467-024-53225-1. PubMed PMID: 39557836; PubMed Central PMCID: PMC11574202. †Denotes co-corresponding authors
Zhang H, Tsui CK, Garcia G, Joe LK, Wu H, Maruichi A, Fan W, Pandovski S, Yoon PH, Webster BM, Durieux J, Frankino PA, Higuchi-Sanabria R, Dillin A. The extracellular matrix integrates mitochondrial homeostasis. Cell. 2024 Aug 8;187(16):4289-4304.e26. doi: 10.1016/j.cell.2024.05.057. Epub 2024 Jun 27. PubMed PMID: 38942015.
Shen K, Durieux J, Mena CG, Webster BM, Tsui CK, Zhang H, Joe L, Berendzen KM, Dillin A. The germline coordinates mitokine signaling. Cell. 2024 Aug 22;187(17):4605-4620.e17. doi: 10.1016/j.cell.2024.06.010. Epub 2024 Jul 2. PubMed PMID: 38959891.
Ruetz TJ, Pogson AN, Kashiwagi CM, Gagnon SD, Morton B, Sun ED, Na J, Yeo RW, Leeman DS, Morgens DW, Tsui CK, Li A, Bassik MC, Brunet A. CRISPR-Cas9 screens reveal regulators of ageing in neural stem cells. Nature. 2024 Oct;634(8036):1150-1159. doi: 10.1038/s41586-024-07972-2. Epub 2024 Oct 2. PubMed PMID: 39358505; PubMed Central PMCID: PMC11525198.
Garcia G, Zhang H, Moreno S, Tsui CK, Webster BM, Higuchi-Sanabria R, Dillin A. Lipid homeostasis is essential for a maximal ER stress response. Elife. 2023 Jul 25;12. doi: 10.7554/eLife.83884. PubMed PMID: 37489956; PubMed Central PMCID: PMC10368420.
Moehle EA*, Higuchi-Sanabria R*, Tsui CK, Homentcovschi S, Tharp KM, Zhang H, Chi H, Joe L, de Los Rios Rogers M, Sahay A, Kelet N, Benitez C, Bar-Ziv R, Garcia G, Shen K, Frankino PA, Schinzel RT, Shalem O, Dillin A. Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization. Sci Adv. 2021 Oct 29;7(44):eabj6818. doi: 10.1126/sciadv.abj6818. Epub 2021 Oct 29. PubMed PMID: 34714674; PubMed Central PMCID: PMC8555897. *Denotes equal contribution
Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC. CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity. Nat Chem Biol. 2019 Oct;15(10):949-958. doi: 10.1038/s41589-019-0342-2. Epub 2019 Aug 26. PubMed PMID: 31451760; PubMed Central PMCID: PMC6911768.
Please see Dr. Tsui’s Google Scholar for full publication list.
